The B7 Homolog Butyrophilin BTN2A1 Is a Novel Ligand for DC-SIGN
نویسندگان
چکیده
منابع مشابه
The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.
The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein related to the extended family of B7 costimulatory molecules. BTN2A1 mRNA was expressed in most human tissues, but protein expression was significantly lower in leukocytes. An Ig-fusion protein of BTN2A1 bound to immature monocyte-derived dendritic cells. Binding diminished upon MoDC maturation and no binding was detected to L...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2007
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.179.6.3804